Three Guys Subs & Pizza in South Carolina — What to Order and Where to Find Them

Three Guys Subs & Pizza serves Sicilian-style square pizza and Italian sandwiches across South Carolina locations

Three Guys Subs & Pizza is a regional chain built around two things: thick, airy Sicilian pizza baked in rectangular pans and Italian cold-cut sandwiches on fresh bread. The chain operates multiple locations throughout South Carolina, each one a casual counter-service spot where you order at the register and grab a table or take your food to go. The pizza arrives hot with a crispy bottom and a pillowy interior, and the subs come loaded with quality meats and dressed simply — lettuce, tomato, onion, oil and vinegar, no pretense.

The name comes from the original concept: three guys running a straightforward operation focused on doing two things well rather than a sprawling menu. That philosophy has held through the expansion. You won't find elaborate specialty pizzas or gourmet toppings here. What you get is consistency — the same Sicilian crust, the same sandwich formula, the same casual atmosphere across every location.

Key Takeaways

• Three Guys specializes in Sicilian-style square pizza with a thick, airy crust and Italian cold-cut sandwiches, both available at multiple South Carolina locations.
• The menu is intentionally limited to pizza, subs, and a few sides, which keeps quality high and wait times short.
• Most locations operate as counter-service with casual seating, making it a quick lunch or dinner stop rather than a sit-down restaurant.
• Prices are moderate for the portion size — a large Sicilian pizza and a sub make a full meal for two people without spending much.

What to order: the pizza and the subs

The Sicilian pizza is the signature item. It comes in a rectangular pan, typically sold by the slice or as a whole pie. The dough is thicker than New York-style pizza but not as thick as Detroit-style — somewhere in the middle, with enough air pockets to feel light despite the size. The crust gets crispy on the bottom from the pan and stays soft inside. Toppings are applied generously but not buried under cheese, so you taste the sauce and the toppings equally.

The Italian subs are built on fresh bread that arrives daily from local bakeries at most locations. A standard sub combines capicola, ham, and provolone, dressed with lettuce, tomato, onion, oil, vinegar, and oregano. The bread is the foundation — if it's not fresh, the sandwich falls apart. Three Guys treats it as such. You can build your own or order a named combination. Portions are generous; a regular sub is a full meal.

Beyond those two, the menu includes wings, salads, and a few pasta dishes at some locations, but the pizza and subs are what people come for. Sides like garlic knots or breadsticks round out an order without demanding attention.

Where Three Guys locations are in South Carolina

Three Guys operates in the Midlands and Lowcountry regions, with the heaviest concentration in and around Columbia. Locations exist in Charleston, Greenville, and several smaller towns, though the chain is not statewide. Each location maintains the same operational style and menu, so the experience is consistent whether you're in the capital or the coast.

Hours vary by location but typically run lunch through dinner, seven days a week. Many locations close by 10 p.m., making this a daytime and early-evening spot rather than a late-night option. Call ahead or check the specific location's hours before you go, especially on Sundays or holidays.

Pricing and portion size

A large Sicilian pizza runs in the mid-range for pizza pricing in South Carolina — more than a chain pizza, less than a high-end pizzeria. A regular Italian sub costs roughly the same as a sandwich at a dedicated sub shop. Together, a pizza and a sub feed two people comfortably for under $30 before tax and tip.

The portions justify the price. A slice of Sicilian pizza is substantial — the rectangular cut means each piece is wider and heavier than a triangular slice from a round pie. A regular sub is 10 to 12 inches and packed with meat and vegetables. You're not paying for a small portion dressed up with presentation.

The casual atmosphere and counter service

Three Guys locations are not designed for lingering. You order at the counter, pay, grab a number, and wait for your food. Most locations have a handful of tables and some bar seating along a window. The walls are usually decorated with photos of the owners, local sports memorabilia, or simple signage. The noise level is moderate — people talking, the kitchen working, but not loud enough to prevent conversation.

This is a grab-and-go spot or a quick lunch destination, not a date-night restaurant. Families with kids fit in easily. The casual vibe means you can show up in work clothes or gym clothes without feeling out of place. Takeout is common and moves quickly.

How Three Guys compares to other South Carolina pizza spots

South Carolina has no shortage of pizza options — from national chains to independent pizzerias to New York-style shops. Three Guys occupies a middle ground: more distinctive than a chain, more casual than a full-service pizzeria, and focused on Sicilian style rather than the Neapolitan or New York traditions that dominate the state.

If you're used to thin-crust New York pizza, Sicilian will feel heavier and more bread-forward. If you're looking for wood-fired Neapolitan, Three Guys won't deliver that. But if you want a thick, airy crust with good toppings and a fast transaction, or if you want a quality Italian sub without fuss, it's a reliable choice. The consistency across locations means you know what you're getting whether you're in Columbia or Charleston.

Frequently Asked Questions

Can I order Three Guys pizza for delivery?

Most locations offer delivery through third-party apps like DoorDash and Uber Eats, though you can also call the location directly to order for pickup or delivery. Delivery times vary by location and demand. Calling ahead is faster than using an app if you're in a hurry.

Do they have vegetarian pizza options?

Yes. You can order a cheese pizza or build your own with vegetables like peppers, onions, mushrooms, and olives. The Sicilian crust works well with vegetable toppings because the bread itself has enough flavor to stand on its own.

What's the difference between a regular and large sub?

A regular sub is typically 10 to 12 inches and feeds one person as a full meal. A large is longer and thicker, designed for two people or a very hungry person. Prices scale accordingly. Most people find a regular sub sufficient for lunch or dinner.

Is Three Guys good for groups or parties?

Yes, though you'll want to call ahead. Most locations can handle group orders for pickup, and you can order multiple pizzas and subs to feed a crowd. The casual seating means groups of more than four or five might not have enough table space to sit together, so takeout is often the better option for larger parties.

Do they use fresh ingredients?

Three Guys sources bread daily from local bakeries at most locations and uses standard Italian cold cuts and cheeses. The focus is on quality basics rather than specialty or organic sourcing. Ingredients are fresh but not marketed as premium or locally grown.