Anthony's Pizza in South Carolina — Where to Find It and What to Order

Anthony's Pizza locations and what makes them stand out

Anthony's is a regional pizza chain with locations across South Carolina, known for Sicilian-style pizza and a casual neighborhood atmosphere. The chain operates multiple locations in the Lowcountry and beyond, each one a gathering spot for families, groups, and regulars who come back for the same pies they've ordered for years. Unlike national chains, Anthony's has kept its menu and approach consistent — thick-crust pizza, fresh toppings, and portions that reflect the owner's Italian heritage.

The restaurants themselves tend toward the unpretentious: red-and-white checkered tablecloths, wood-paneled walls, and a bar area where you can watch the kitchen work. The vibe is deliberately old-school, and that's the point. You're not paying for design or concept; you're paying for pizza that tastes like someone's been making it the same way for decades.

Key Takeaways

• Anthony's serves Sicilian-style pizza with a thick, airy crust that differs from thin-crust New York or Neapolitan styles.
• Multiple Anthony's locations operate across South Carolina, so you can find one near you by searching online or calling ahead.
• The menu includes pizza, pasta, sandwiches, and appetizers, with most locations offering dine-in, takeout, and delivery.
• Prices are moderate for a sit-down pizza restaurant, and portions are large enough that one pie often feeds two people comfortably.
• Anthony's does not take reservations at most locations, so expect a wait during peak dinner hours on weekends.

What to order and how the menu is organized

The pizza menu at Anthony's runs from basic cheese to loaded combinations. You can build your own or order a signature pie — names vary by location, but expect options like "The Godfather," "The Sicilian," or regional specials. Toppings include standard choices (pepperoni, sausage, mushrooms, peppers) and less common ones depending on the location. Most Anthony's locations allow you to choose thin or thick crust, though the thick Sicilian crust is what the restaurant is known for.

Beyond pizza, the menu typically includes pasta dishes (lasagna, baked ziti, spaghetti with meatballs), Italian sandwiches, calzones, and appetizers like garlic knots or fried calamari. Salads are available but not the focus. Desserts usually include tiramisu or spumoni ice cream. Soft drinks, beer, and wine are standard; some locations have a full bar.

Sizes vary by location but generally start at small (personal or 10-inch) and go up to large (16-inch or 18-inch). A large Sicilian pizza is thicker and heavier than a large thin-crust pie, so one large often serves two people or a family of three with leftovers.

How to find your nearest Anthony's and hours of operation

Anthony's locations are concentrated in the Charleston area and surrounding regions, though the chain has expanded to other parts of South Carolina over the years. The easiest way to find a location near you is to search "Anthony's Pizza South Carolina" online or call directory assistance. Most locations have their own phone numbers and websites, though they may not all maintain active social media pages.

Hours typically run from late morning (11 a.m. or noon) through late evening (10 p.m. or 11 p.m.), with reduced hours on Sundays. Some locations close on Mondays. Call ahead to confirm hours, especially on holidays or if you're traveling to an unfamiliar location. Delivery and takeout availability depend on the individual restaurant, so ask when you call.

Dine-in, takeout, and delivery options

Most Anthony's locations offer all three: dine-in seating in the restaurant, takeout orders you pick up yourself, and delivery to your home or office. Dine-in is the traditional experience — you sit at a table, order from a server, and eat in the restaurant. Takeout means you call or order online, pick up your food at the counter, and take it home. Delivery is available from some locations through their own drivers or third-party apps, though availability and fees vary.

If you're ordering for a group or party, call the restaurant directly rather than using an app. Many Anthony's locations will give you a discount for large orders or can prepare food ahead if you give them notice. Ask about party platters or family-size combinations when you call.

Pricing and what to expect to spend

A large pizza at Anthony's typically costs between $15 and $25, depending on toppings and location. A small or personal pizza runs $8 to $15. Pasta dishes are usually $12 to $18. Sandwiches and appetizers fall in the $6 to $12 range. Delivery fees, if applicable, add $2 to $5 to your order. Tax is not included in these prices.

Anthony's is moderately priced for a sit-down Italian restaurant — more expensive than a chain like Domino's, less expensive than a fine-dining Italian place. If you're on a tight budget, one large pizza and a salad or appetizer can feed a family of four. Leftovers keep well and reheat easily, especially the thick Sicilian crust.

Parking and accessibility

Most Anthony's locations have their own parking lot or street parking nearby. Parking is usually free and plentiful except during peak dinner hours (Friday and Saturday evenings). Call ahead if you have mobility concerns and want to confirm that the location has accessible parking and entrances.

The restaurants themselves are casual and not fancy, so there's no dress code. Families with children are common, and most locations are comfortable with kids. High chairs and booster seats are typically available, though it's worth calling ahead to confirm.

Why Anthony's has lasted in South Carolina

Anthony's has survived and grown in a market flooded with national pizza chains because it does one thing well and doesn't try to be everything. The Sicilian crust — thick, airy, and slightly crispy on the edges — is distinctive enough that people remember it and come back for it. The sauce and cheese are straightforward, not trendy. The prices are fair. The locations feel like neighborhood restaurants, not corporate outposts.

In South Carolina's food culture, where tradition and consistency matter, Anthony's fits. It's the kind of place where families have celebrated birthdays for two generations, where coworkers grab lunch on Fridays, where you know what you're getting before you walk in. That reliability is harder to find than it sounds, and it's why Anthony's has a loyal following across the state.

Frequently Asked Questions

Can I order Anthony's pizza online?

Some Anthony's locations take orders through their own websites or phone lines, while others may be listed on third-party delivery apps. Call the location nearest you to ask whether online ordering is available and whether they deliver to your address. Ordering by phone directly with the restaurant often gets you faster service and may avoid app fees.

Does Anthony's take reservations?

Most Anthony's locations operate on a first-come, first-served basis and do not take reservations. During peak hours (Friday and Saturday evenings), expect a wait of 20 to 45 minutes. If you're bringing a large group, call ahead to let them know you're coming — they may be able to hold a table or prepare your food faster.

What's the difference between Anthony's thin crust and thick crust?

The thick crust is Sicilian-style — airy, about an inch tall, and slightly crispy on the bottom. The thin crust is flatter and crispier throughout. The thick crust holds up better to heavy toppings and is what Anthony's is known for, but both are available at most locations. Try the thick crust at least once to understand why regulars prefer it.

Are there vegetarian options at Anthony's?

Yes. You can order a cheese pizza or build your own with vegetable toppings like mushrooms, peppers, onions, olives, and tomatoes. Pasta dishes with marinara sauce are also vegetarian. Call ahead if you need to confirm that the kitchen can prepare food without meat or meat-based broths.

Does Anthony's cater or do party orders?

Many locations will prepare large orders for parties, meetings, or events. Call the restaurant directly to discuss your needs, the number of people, and any special requests. They can often give you a better price on bulk orders than you'd pay ordering individual pizzas, and they may be able to prepare food ahead if you give them advance notice.